Boston Scientific buys Vessix for blood pressure device
















(Reuters) – Boston Scientific Corp said on Thursday it will acquire privately-held Vessix Vascular Inc, a developer of a catheter-based device that treats high blood pressure by deadening nerves near the kidneys.


Under the terms of the deal, expected to close at the end of November, Boston Scientific will make an upfront payment of $ 125 million, plus milestone payments of up to $ 400 million between 2013 and 2017. The deal is expected to be immaterial to adjusted earnings in 2013 and 2014, and break-even to profitable thereafter.













One in three adults in the United States has high blood pressure, according to the National Institutes of Health.


Health officials say more than one billion people in the world suffer from the ailment, also known as hypertension, which can lead to coronary heart disease, heart failure, stroke, kidney failure, and other health problems.


Normal blood pressure is below 120/80 mmHg (millimeters of mercury). Hypertension is a reading above 140/90 mmHg.


Despite widespread availability of drugs to treat the condition, blood pressure in many patients remains uncontrolled.


Renal denervation is a procedure in which a thin, flexible catheter is threaded through the body to the renal sympathetic nerves near the kidneys. Radiofrequency energy is delivered to disrupt the nerve activity, relieving high blood pressure.


Renal denervation is expected to be a multibillion dollar market by 2020, according to Boston Scientific, a maker of heart pacemakers, implantable defibrillators and heart stents.


The new therapy is not yet approved in the United States, but several products are available in Europe.


Device makers that have received approval to sell hypertension devices in Europe include frontrunner Medtronic Inc, St Jude Medical Inc, Covidien Plc, ReCor Medical and Vessix, which also has approval in Australia.


“We think the acquisition of Vessix is strategically important as it provides Boston Scientific an entrance point into the valuable renal denervation market and it does so with a product that we think has advantages that will likely make it a viable competitor,” said Wells Fargo analyst Larry Biegelsen, who characterized the market as overcrowded.


Boston Scientific shares were trading at $ 5.16 on the New York Stock Exchange, unchanged from Wednesday’s close.


(Reporting By Debra Sherman; Editing by Jeffrey Benkoe)


Medications/Drugs News Headlines – Yahoo! News



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Bank refrains from new stimulus

















The Bank of England has decided not to extend its quantitative easing (QE) stimulus programme, which has injected £375bn into the UK financial system.













Under QE, the Bank creates money and uses it to buy government bonds to try to stimulate the economy.


The Bank’s Monetary Policy Committee (MPC) also decided to keep interest rates at 0.5%, the record low they have been held at since March 2009.


The UK came out of recession recently, growing 1% between July and September.


But a succession of poor economic indicators and corporate results has led many observers to believe that the economy is still weak, leading to speculation that more QE would be needed.


Indeed, the minutes from the last MPC meeting in October showed that some members thought more QE would be required at some point in the future.


“We are pretty sure that the economy will need more stimulus in the months ahead,” said Vicky Redwood of Capital Economics.


“And we do not think that the committee is out of firepower yet.”


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The best credit rating that can be given to a borrower’s debts, indicating that the risk of borrowing defaulting is minuscule.




On Wednesday, the European Commission cut its 2013 eurozone growth forecast from 1% to just 0.1% and said it expected unemployment to continue rising next year.


As about half of Britain’s trade is with Europe, the commission’s forecast, if accurate, could have a significant knock-on effect for the UK.


But the jury is out on whether QE is effective enough at stimulating consumer spending and business investment.


In July, the Bank launched its Funding for Lending Scheme (FLS), aimed at encouraging banks and building societies to increase the size and frequency of loans they make to consumers and small businesses.


Under FLS, the Bank lends money to the financial institutions at below market rates, and offers a better deal to those who make the most loans.


As yet there is no published data showing how well the scheme is going.


However, on Friday the Bank is due to release statistics showing the lending rates being offered by financial institutions, and a general lowering of rates could indicate that FLS is beginning to work.


BBC News – Business



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Ghana building collapse traps dozens, kills 1
















ACCRA, Ghana (AP) — A five-story shopping center built earlier this year in a bustling suburb of Ghana‘s capital collapsed Wednesday, killing at least one person and leaving several dozen people trapped in the rubble, authorities and eyewitnesses said.


Rescue crews used cranes to try and remove debris from the top of the building amid fears that machinery sifting through the wreckage could injure trapped survivors. Crowds of bystanders gathered as rescuers sifted through cement and glass.













The fatality at the Melcom Shopping Center at Achimota, a suburb of Accra, was confirmed by Public Affairs Officer of the Ghana Fire Service Billy Anaglate. “We are still working to find out the fate of others who may be trapped under,” he said.


Other officials told The Associated Press that the death toll was likely to rise.


An AP reporter at the scene saw at least one man pulled from the debris, covered in dust and who was then whisked into an ambulance.


A Greater Accra Regional Public Affairs officer, deputy superintendent Freeman Tettey, confirmed that one person died and told the AP that 51 have been rescued and sent to hospitals around the capital.


“I was on my way to the shop when l saw it crumpling down,” Kojo Boadi, an eyewitness, said.


President John Mahama declared the scene a disaster zone and cut short his election campaign in the north of the country to be able to visit the site. The presidential election is scheduled for December.


The five-story store opened in February is part of the Melcom chain owned by Indian immigrant magnate, Bhagwan Khubchandani. His late father arrived in Ghana in 1929 as a 14-year-old to work as a store boy in the-then Gold Coast.


The store sells a variety of cheap, imported household goods and appliances that are popular with working-class Ghanaians.


Africa News Headlines – Yahoo! News



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Foxconn’s Gou says tough to cope with iPhone demand
















TAIPEI (Reuters) – Taiwan’s Foxconn Technology Group said on Wednesday the company’s flagship Hon Hai unit is finding it difficult to cope with the massive demand for Apple Inc‘s iPhones.


“It’s not easy to make the iPhones. We are falling short of meeting the huge demand,” Foxconn Chairman Terry Gou told reporters after a business forum.













However, he declined to comment on brokerage reports saying that the group’s other unit, Foxconn International Holdings (FIH), had taken on some production.


Hon Hai Precision Industry, the main listed entity of the parent Foxconn Technology Group, is the key assembler of Apple’s iPhones.


The group also owns FIH, which traditionally assembles non-Apple products, such as phones from Nokia Oyj and Huawei Technologies Co Ltd.


Shares of Foxconn International Holdings Ltd (FIH), the world’s biggest contract maker of cellphones, surged as much as 35 percent on Monday after Citigroup upgraded the stock to a ‘buy’ and said it expected the firm to start assembling iPhones this year.


Shares of FIH fell 5.7 percent in Hong Kong on Wednesday, while Hon Hai was up 0.6 percent in Taipei. (Reporting by Clare Jim and Lee Chyen yee; Editing by Anne Marie Roantree)


Tech News Headlines – Yahoo! News



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MTV Launches Fundraiser for “Jersey Shore” Site Ravaged by Sandy
















LOS ANGELES (TheWrap.com) – “Jersey Shore” might be wrapping up its run, but the spirit of goodwill and humanity that the MTV reality hit has inspired will carry on.


MTV will air a one-hour fundraising special to help out Seaside Heights, N.J., the site where Snooki and her fellow orange-hued revelers played out most of their televised shenanigans, and was ravaged by Hurricane Sandy last week.













The one-hour special, “Restore the Shore,” will air live on November 15 at 11 p.m., with a tape delay for the west coast.


The special, which will also run in online and mobile formats, will feature the “Jersey Shore” cast as well as other special guests, and air from MTV’s Times Square studio in New York.


MTV is partnering with nonprofit organization Architecture for Humanity for the fundraising effort, with efforts primarily focused on rebuilding the Seaside Heights boardwalk, with additional assistance going to re-building efforts for businesses and residents in the community.


TV News Headlines – Yahoo! News



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Researchers Link High Blood Pressure to Brain Aging
















California scientists have reported structural changes in the brains of adult patients who are relatively young and who also suffer from hypertension. Their findings directly link high blood pressure to brain aging.


The project, led by University of California Davis researchers, is the first to demonstrate this relationship in people just entering middle age, according to Medical News Today (MNT). Prior studies followed older patients.













Hypertension — high blood pressure — occurs when the force of a person’s blood against artery walls is high enough to cause medical problems, the Mayo Clinic says. A majority of patients have no symptoms. Among the complications are heart attacks, strokes, aneurysms, heart failure, issues with blood vessels in the kidneys and eyes, cognitive problems, and metabolic syndrome.


A normal blood pressure reading is 120/80. Pre-hypertension readings range from 120 to 139/80 to 89. Readings higher than 140/90 are considered high blood pressure.


Earlier studies demonstrated a relationship between high blood pressure and an elevated risk of brain injury, atrophy leading to brain processing problems, and dementia. The California researchers concluded that treating high blood pressure during middle age — years before most people think much about it — can help prevent cognitive problems later.


The scientists followed 579 subjects in the Framingham Heart Study. Most were in their late 30s when they joined the study in 2009.


Subjects were placed into one of three groups: normal blood pressure, pre-hypertensive, or high blood pressure. The researchers noted whether each was a smoker or took medication for blood pressure. Subjects then underwent MRIs of their brains, including measurements of any injury to white or gray matter.


According to the National Institute of Mental Health, gray matter is comprised of cell bodies of neurons that talk to each other. White matter, says MNT, makes up the brain’s axons, long strands that transport electrical signals. Various imaging studies allowed the researchers to compare brains of the three blood pressure groups.


Among subjects with high blood pressure, brains were significantly less healthy and looked older than those of patients with normal blood pressure. In fact, the brain of a 33-year-old subject in the first group resembled that of a typical 40-year-old in the normal group. Subjects with high blood pressure on average had nine percent less gray matter in their frontal and temporal lobes than patients in the normal group.


I was shocked to discover in my late 30s that I had high blood pressure. During an appointment with a new gynecologist, my readings soared to 154/97 even though I had no symptoms. He immediately sent me across the street to see an internist. This fortunate intervention led to the need to monitor my numbers daily and permanent medication. Beyond protecting me from the most common complications of hypertension, it might well have prevented premature aging of my brain.


Vonda J. Sines has published thousands of print and online health and medical articles. She specializes in diseases and other conditions that affect the quality of life.


Health News Headlines – Yahoo! News



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The Next Four Years: Obama’s Steady, Slo-Mo Recovery
















President Barack Obama promises to use his second term to boost the U.S. economy. The opposite is more like it: A strengthening economy will boost the president’s second term. The likelihood of continued job growth will increase tax revenue, which will make it easier to shrink the budget deficit while keeping taxes low and preserving essential spending. All this will occur without any magic emanating from the Oval Office. In fact, it would have occurred if Mitt Romney had been elected president. “The economy’s operating well below potential and there’s a lot of room for growth” whoever is in office, says Mark Zandi, chief economist of forecaster Moody’s Analytics (MCO).


Something could still go wrong, but the median prediction of 37 economists surveyed by Blue Chip Economic Indicators is that over the next four years, economic growth will gather momentum as jobless people go back to work and unused machinery is put back into service. “The self-correcting forces in the economy will prevail,” predicts Ben Herzon, senior economist at Macroeconomic Advisers, a forecasting firm in St. Louis.













By a range of indicators, the economy is better situated for growth today than it’s been in years. Banks have strengthened their balance sheets. Most households, which borrowed too much during the housing bubble, have gotten their debt back to normal levels through a combination of frugality and default. Upper-income households’ balance sheets “are as pristine as they’ve ever been,” although mortgage debt remains a heavy burden at lower income levels, Zandi says. Housing prices have gone from falling to rising, buoying confidence. Increased consumer spending should induce more business investment in a virtuous circle. And there’s pent-up demand for residential and commercial construction.


That’s not to say that growth will be gangbusters. In fact, it may not even be strong enough to get the U.S. back to full employment by the time the president’s second term comes to an end.


Obama worked hard during the campaign to persuade voters that he should not be held responsible for the weakness of the economy. Voters apparently listened: Not since Franklin D. Roosevelt has a president been reelected with the unemployment rate as high as it is now, 7.9 percent as of October.


By the same token, Obama can’t claim all the credit for the recovery that began slowly in June 2009 and is on track to continue through his second term.


Most economists say that the influence of the president, any president, over a nearly $ 16 trillion economy is smaller than commonly believed. “Knowing who’s going to be president takes you only about 10 percent of the way,” says Robert Shapiro, a Democratic adviser who is chairman of Sonecon, a Washington-based economic consultancy.


Even Obama’s own former chief economic adviser, Austan Goolsbee, once said that: “Most all of the economy has nothing to do with the government.”


Presidents’ policy choices do matter during crises, like the one that greeted Obama when he took office in January 2009. As the president never tires of pointing out, the U.S. was losing about 800,000 jobs a month. Moody’s Zandi, who advised Republican candidate John McCain during the 2008 presidential campaign, argues that “what Obama did with regard to fiscal policy [in 2009] was critical to avoiding a depression.” A Republican president might have acted less aggressively and allowed the economy to tank.


Derring-do is no longer essential. “The economy needs less support from the government in the coming four years than in the past four years,” says Harm Bandholz, chief U.S. economist of UniCredit (UCG), a European banking group.


In any case, contrary to what both campaigns argued, Obama’s second term won’t look that different from what would have been Romney’s first when it comes to the factors that affect the overall economy. Federal deficits ballooned to over $ 1 trillion in each of the past four fiscal years because the deepest recession since World War II forced up government spending while depressing tax revenue. Things will start getting back to normal in the coming term as the economy continues to revive and more working people pay taxes. The nonpartisan Congressional Budget Office predicts that even without any increase in tax rates (except for the scheduled expiration of the payroll tax break), federal revenues will jump 38 percent by 2016.


Both candidates promised to cut deficits by similar amounts. Romney vowed to cut taxes across the board and shrink the budget deficit entirely through spending cuts; Obama also plans to rely heavily on spending cuts, though he says he’ll get a quarter of the action through higher taxes. That distinction, while important to individual constituents, matters much less to economic forecasters.


The same goes for spending choices. Where the dollars go is of intense concern to lobbyists for defense contractors, farmers, and the like, but relatively unimportant to forecasters, who focus on the overall balance of spending and revenue more than its composition. Deficits could actually be smaller under Obama than they would have been under Romney—who, like George W. Bush, might have gotten Congress to give him lots of tax cuts but not so many spending cuts.


It’s telling that the major economic forecasters didn’t bother creating separate scenarios for an Obama win vs. a Romney win. The differences were too small to justify the effort.


Forecasters do care—a lot—about monetary policy, because interest rates have a big influence on economic activity. But the easy-money policy of the past four years is likely to continue throughout Obama’s second term. Wall Street was nervous that a President Romney would appoint an inflation hawk such as his adviser, Hoover Institution economist John Taylor, to replace Chairman Ben Bernanke when Bernanke’s term ends in January 2014. Obama will probably pick someone more in Bernanke’s mold, such as Vice Chairman Janet Yellen. Bottom line: little or no change.


So what will drive economic growth over the coming four years? Mostly the natural healing process.


The Fed’s rate-setting Federal Open Market Committee pegs the economy’s long-run potential growth rate at 2.3 percent to 2.5 percent. But growth is likely to exceed that pace slightly for the next few years as unused labor and capital get put back into service. Blue Chip Economic Indicators says the average forecast of economists it surveys is for growth of about 3 percent in 2014, 2015, and 2016, with the unemployment rate gradually sinking over the period from 7.4 percent to 6.9 percent to 6.5 percent.


Notice that the 6.5 percent unemployment predicted for Obama’s last year in office, while better, is still above the historical average. Blue Chip’s survey doesn’t have the jobless rate under 6 percent until 2019, showing just how long it takes for the economy to recover from a severe blow like the 2007-09 recession.


It’s possible growth could beat expectations by the end of Obama’s second term—but the economy may just as easily underperform. Growth forecasts are predicated on the assumption that the federal government keeps the confidence of the world’s investors by putting itself on a plausible path to long-term financial stability. Putting off spending cuts made sense when the economy was weak and vulnerable, but if Congress and the White House continue to avoid taking bad medicine when the economy is in better shape, bond investors may lose confidence and demand to be paid higher yields on America’s $ 11 trillion mountain of publicly held debt.


The state of the world economy will affect the U.S.’s prospects too, and there the American president has even less influence than he does at home. If Europe’s crisis gets bad enough, it could damage the U.S. financial system—payback for the harm that the U.S. did in 2008 after the Lehman Brothers crisis. Maybe a hard landing in China will disrupt global growth. Or war in the Middle East will cause an oil shock.


Even if none of that happens, job growth will be constrained by globalization, says John Silvia, chief economist of Wells Fargo Securities (WFC). U.S. companies will continue to satisfy growing foreign demand by building factories abroad, not in the U.S., Silvia says. “The character of the labor market has changed,” he says. “It’s much harder to integrate low-skilled or semi-skilled workers into the economy.”


Sonecon’s Shapiro says that “the central economic problem” of the next four years is to “change the path of earnings” so the benefits of economic growth reach ordinary workers, not just corporations and their shareholders.


Politically speaking, Obama’s biggest advantage is that expectations have been beaten down so far that even so-so economic growth will look pretty darn good to the average American.


For a while, anyway. The biggest risk for Obama is that by 2016, a slo-mo recovery in a socially polarized economy will cease to impress. The crises may be less extreme over the next four years, but the economic challenges are no smaller.


Businessweek.com — Top News



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Canada firms to capitalize on nuclear trade with India
















NEW DELHI (Reuters) – Canadian firms will be able to export uranium and nuclear reactors to India for the first time in almost four decades under an agreement between the two nations, their prime ministers said, but more work is needed to implement the deal.


Once implemented, the agreement will end a ban on nuclear cooperation Canada imposed in 1976 after India secretly exploded its first nuclear bomb in 1974, commonly called the “Smiling Buddha”, using material from a Canadian-built reactor in India.













“Being able to resolve these issues and move forward is, we believe, a really important economic opportunity for an important Canadian industry, part of the energy industry, that should pay dividends in terms of jobs and growth for Canadians down the road,” Canadian Prime Minister Stephen Harper said on Tuesday on a visit to New Delhi.


A negotiator with the Canadian Nuclear Safety Commission (CNSC), speaking on condition of anonymity because of the delicacy of the talks, said that what remained was a careful legal review of the language; translation into French and Hindi; and then a signing.


This is not expected to take very long, he said. The two sides have set up a joint committee to liaise on nuclear issues, but he said it would not be negotiating.


India aims to lift its nuclear capacity to 63,000 MW in the next 20 years by adding nearly 30 reactors. The country currently operates 20 mostly small reactors at six sites with a capacity of 4,780 MW, or 2 percent of its total power capacity, according to the Nuclear Power Corporation of India Limited.


Canada’s ambassador to India, Stewart Beck, said on Monday his country wanted to be able to track all nuclear material, but that India felt it only needed to report to the International Atomic Energy Agency (IAEA).


It was not clear who made concessions in the talks and how effective the safeguards would be to ensure that Canadian material did not get used again for making nuclear weapons.


However, the CNSC official said India would now be required to notify Canada of any transfers to a third country and trade could only go to facilities that are safeguarded by the IAEA.


PROBABLY BEATING AUSTRALIA


Harper said the CNSC had worked to “achieve all of our objectives in terms of non-proliferation”.


Canada is in a race against Australia, its strategic ally but a commercial rival in the uranium business. Australia is also trying to nail down safeguards under which it too could sell uranium to India.


“We are effectively ahead of the Australians,” the CNSC official said, noting however that Russia and Kazakhstan were already supplying into India.


Opening up the Indian market would be a big help to Canada’s Cameco Corp, which is the world’s largest publicly traded uranium producer but which recently cut its long-term output targets due to the Fukushima disaster.


“Anytime we can reduce the roadblocks to selling our product around the world is always helpful,” Cameco chief executive Tim Gitzel told Reuters in Canada. “It opens a new market for us with the appropriate safeguards in place. So this is good news.”


Another potential beneficiary is Canadian engineering firm SNC Lavalin Group Inc, which bought the government’s commercial nuclear division, which designed the Candu reactor that is in use in numerous countries.


“As far as the sales of reactors goes, we would normally now request that Canada be accorded the same treatment as the Russians, the French and the Americans and that a site be designated in India for the implementation of at least a twin- unit Candu nuclear power station,” SNC Lavalin International President Ronald Denom, part of Harper’s delegation in India, told Reuters.


He also said it should open up the market to service the existing reactors in India.


Harper also said Canada welcomed foreign investment, after the country temporarily blocked Malaysian state oil firm Petronas’ C$ 5.17 billion ($ 5.19 billion) bid for gas producer Progress Energy Resources on October 20.


Late on Friday, Canada extended to December 10 its review of a $ 15.1 billion bid made in July by China’s CNOOC Ltd for Canadian energy producer Nexen Inc.


“Those decisions have to be taken looking at the global evolving economy in which we operate,” Harper said.


($ 1 = C$ 0.9965)


(Additional reporting by Julie Gordon in Toronto; Additional writing by Frank Jack Daniel; Editing by Jonathan Thatcher and Michael Roddy)


Canada News Headlines – Yahoo! News



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News Summary: IDC says Apple tablet share drops
















HEADING DOWN: Apple‘s share of the market for tablet computers fell to 50 percent in the third quarter as the iPad faced more competition.


STILL UP: In the July-September period, Apple shipped 14 million devices, up 26 percent from a year ago. But its share fell because the overall tablet market grew by 50 percent.













FACTORS: Apple had no new tablets out in the third quarter. It also might have seen sales slow amid expectations of a smaller iPad. Apple could regain share in the holiday quarter with last Friday’s release of new iPad devices.


Gadgets News Headlines – Yahoo! News



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Springsteen, Jay-Z put the pop in Obama rally
















COLUMBUS, Ohio (AP) — Someone has to introduce the president.


On Monday, the final day of the presidential campaign, President Barack Obama, however, didn’t bring along an opening act. He brought along two main acts.













Bruce Springsteen. Jay-Z. Theirs wasn’t an introduction, it was pop culture moment.


The Boss was spending the entire day with Obama, traveling on Air Force One from Madison, Wis., to Columbus, Ohio, and then to Des Moines, Iowa, where Obama planned a coda for his campaign, a finale where his run for the presidency began five years ago.


Jay-Z boomed his way into Columbus‘s Nationwide Arena, performing a rendition of his hit “99 Problems” with a political twist for a crowd estimated by fire officials at more than 15,000 people. He changed a key R-rated word to make his own political endorsement. “I got 99 problems but Mitt ain’t one,” he sang.


“They tell the story of what our country is,” Obama said of the two performers, “but also of what it should be and what it can be.”


Springsteen added a whole new sense of vigor, even giddiness, to the Obama entourage, with many of the president’s aides and advisers clearly star-struck by the rocker’s presence.


Springsteen, in jeans, black boots, a work shirt, vest and leather jacket, was not wearing the typical Air Force One attire. But the Obama camp has left formality aside; many aides are growing beards through Election Day and ties have been left behind in favor of sweaters for the chilly outdoor events during the last hours of the campaign.


Asked if there was any downside to using celebrity glitz instead of substance to drive voters to the polls in the final days, Obama spokeswoman Jen Psaki laughed. “I think Bruce Springsteen might be offended by you calling him glitzy,” she said.


“Bruce Springsteen, and some other celebrities who have been helping us, reach a broad audience that sometimes tune out what’s being said by politicians,” she said.


As Psaki spoke to reporters at the back of the plane, Obama was up front and on the phone with New Jersey Gov. Chris Christie discussing the recovery from Superstorm Sandy. Christie, who says he has attended more than 100 Springsteen concerts, said Obama then handed the phone to Springsteen, a New Jersey native whose songs often have been tributes to his youth in the state.


Upon landing in Columbus, Springsteen told a reporter that it was his first trip on Air Force One. Grinning, he said, “It was pretty cool.” As for New Jersey, he said, “I’m feeling pretty hopeful” that the state’s hard-hit shore will recover.


In Madison and Columbus, Springsteen serenaded audiences with renditions of top anthems “No Surrender,” ”Promised Land” and “Land of Hope and Dreams.” But he also has a custom-made campaign song named after the Obama motto “Forward” — which he acknowledged was “not the best I’ve ever written.”


“How many things rhyme with Obama?” he asked.


Obama, no doubt, didn’t mind.


“I’m going to be fine with Bruce Springsteen on the last day that I’ll ever campaign,” he said above the din of the crowd.


“That’s not a bad way to bring it home. With The Boss. With The Boss.”


Entertainment News Headlines – Yahoo! News



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